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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

The circular also stressed zero tolerance for cheating.
曲道奎表示:“随着机器人正逐渐扩至几乎所有领域,我国机器人制造商应当了解自身和外资品牌间的差距,利用中国机器人的蓬勃发展并学习国外经验,以帮助我国由世界最大的机器人市场成长为机器人制造强国。”

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

This is the second time that both enterprises and institutions have adjusted basic pension, since the first simultaneous adjustment in 2016.
“I’m 17 – I want to be with my family and friends and school,” he said. “I’m going to be in London for the foreseeable future.”

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 北京:中介不配合 房源全下架
Open Access Perspective

Soft matter science and the COVID-19 pandemic

新加坡已经连续三次被列为世界上生活成本最贵的城市,但是这一年中城市生活成本在世界范围内的分布有了显著的变化。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

●"Man shoots off his own penis taking selfies with gun"

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

如果一个“推文幼稚的像个幼儿园小朋友”一样最年长的人,都可以当选总统,那为什么反过来不试一下,看看年轻人能否当选并明智地执政?
201001/93725.shtml
Global movie earnings hit a record $38.3b in 2015, with China accounting for $6.8 billion, a nearly 50% increase over the previous year, according to data from the US National Association of Theatre Owners.
我经常生气

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

与此同时,微信恐怕也是腾讯吸引海外用户潜力最大的产品。Forrester的分析师Bryan Wang说,他看到新加坡、印度的同事和朋友也开始出现在了自己的微信好友列表中。
n. 预定,保留意见
反对派是合法的,可以自由表达观点而且权力受到限制。
4.Sex and the City Caused a Rush on Cupcakes

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

2012年,电子烟开始流行,它们的工作原理是通过加热尼古丁的液体,模拟真实的烟。很多人认为电子烟是中国的制药商韩力发明的,他说梦到自己在烟雾缭绕的蒸气中快要窒息后,发明了电子烟。他的父亲死于吸烟引起的肺癌。他自己也是一个不折不扣的瘾君子,他曾尝试使用尼古丁贴片来戒烟,但失败了。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 房企8月销售面积普遍下滑
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

LBS tops the ranking of the best 81 business schools in Europe based on the schools’ performance in four of the rankings published by the FT each year: MBA, executive MBA (EMBA), masters in management (MiM) and executive education. (Two schools tied for 80th position with identical scores.)

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Of the large land areas where many people live, only the eastern portion of the United States recorded below-average temperatures in 2014, in sharp contrast to the unusual heat in the West. Some experts think the weather pattern that produced those American extremes is an indirect consequence of the release of greenhouse gases, though that is not proven.
After Zhou contaminated the water, one of Zhou's classmates surnamed Tang noticed that the water coming out of the dispenser was milky and had a pungent scent.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

各类公司均表示要扩充高级系统分析师队伍。与今年的薪酬水平相比,这一职位的起薪预计会增长5%,达到8.55万美元;大型企业中,金融分析师的起薪将达到8.15万美元,比2010年增长4.8%;经验丰富的行政助理的薪水也将上涨3.1%,达到4.175万美元。
Beijing has responded with increasing rancour against Seoul’s decision to deploy Thaad, the Terminal High Altitude Area Defence platform. While South Korea insists the system is for defending itself against North Korean missiles, China fears the technology will allow an ally of the US to spy on its military developments.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

或许,在纽约尼克斯夺取NBA总冠军的道路上,缺失的关键就是甜瓜(安东尼的昵称)。噢,不,等等,林书豪才是他们欠缺的一环。然而,无论怎样,甜瓜不会妨碍尼克斯的冠军梦。
Zhang Guoli to host 2014 Spring Festival Gala

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Sure, it plays music, has a calendar, and even entertains the kids, but it could probably also get hacked — just like everything else.
Rounding out the top three is Fleetwood Mac at $59.5 million. Though the band contains three men, it also boasts two high-profile ladies—Stevie Nicks and the recently-returned Christine McVie—rendering the group eligible for this list. Its On With The Show tour included 86 concerts during our scoring period, grossing well over $1 million per city.
《风流医生俏护士》首播时,鹰眼和诱捕者这两个角色原本同等重要,也正是在这样的条件下,韦恩·罗杰斯才同意扮演诱捕者约翰。然而,当艾伦·艾尔达开始对这个角色进行改动并对整个剧情走向产生更大影响时,鹰眼使诱捕者这一角色黯然失色。
His eloquent defence of equality came after a year of faltering progress on gay marriage in the US and as arguments rage about the lack of diversity among the people running the Silicon Valley companies, including Apple, who shape so much of our culture.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

The advantages for schools seem clear: they enjoy the benefits of bright graduates who would otherwise have gone straight into consulting.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

中国的商业银行是金融体系的控制中心,为实体经济提供的融资占总量的近70%。
惊险、欢快与不安交替进行,乔纳森·格雷泽导演的非凡之处在于让色情电影难得的实现了幻想与现实的融合。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

My grandmother’s favorite poem was Invictus by William Ernest Henley. My father hung a copy of it on our kitchen wall, so I grew up reading it every day: “I am the master of my fate; I am the captain of my soul.” I think the best advice I can give anyone – especially someone just starting out in business – is to embrace your role as master of your own fate. Recognize opportunities when they arise and get comfortable saying “Yes.”

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Stripping out price, volumes of Chinese imports in October fell a more modest 2.6 per cent from a year earlier, according to estimates from Oxford Economics.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

n. 肩膀,肩部
Three Billboards Outside Ebbing, Missouri
鲁纳尔说:这颗钻石可能产于南非的普列米尔矿山,现称库里南矿场。”
反对:影片可能太过非主流,不具有获得大奖的影响力。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

会,即便真实的GDP增速未超过这个数字。关于中国真正的(相对官方数据而言)GDP增长率的猜测,已经衍生出一个由相关经济学专家组成的作坊式行业。官方数据看似稳定而美好——有人怀疑中国有关部门对数据进行了“美化”,调整了一些数字、使其符合增长目标。因此,即使2018年中国的增长磕磕绊绊,官方的增速也几乎肯定会高于预定的6.5%。
《少年收容所》(Short Term 12)是独立制片的小型影片之一,然而却会大大地影响观众。这部低成本电影片长仅96分钟,背景是一个针对问题青少年的收容设施。然而德斯汀?克里顿(Destin Cretton)的导演和布里?拉尔森(Brie Larson)的表演让这部电影跻身年度最佳影片之列。拉尔森几乎可以肯定无缘奥斯卡奖(今年的竞争异常激烈),但她对所扮演的女主角格蕾丝(Grace)的刻画极具水准,格蕾丝是一名20多岁的年轻保育员,她自己的生活远非平静无波。
陆金所是最大的一家。它是中国平安保险(Ping An Insurance)的子公司,平安也是陆金所最大的股东。
This was never more powerful than when he talked publicly for the first time about his sexuality.
So far this year, companies have announced 376 share-repurchase initiatives for a total of $261 billion, according to data from Birinyi Associates. That's nearly 72% higher than 2012, though slightly lower when compared to the same period in 2013, which was a record year for buybacks.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

4. 西班牙企业学院
The truth is, to shut our door to the outside world would not help China do its own things well, so China will continue to open to the outside world, with this opening-up being a gradual process.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

Wishing you happiness during the holidays and throughout the New Year.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
From the themed collection: 建筑建材业:涨价带来投资机会
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

In response, Mr Wilders labelled Mr Rutte a liar, citing the prime minister’s broken pledge not to support a bailout of Greece during the 2012 election.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
From the themed collection: 家居行业带动北京首季消费增长
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

7. 《出局:禁止接触》(Out 1: Noli Me Tangere),导演:雅克·里维特(Jacques Rivette)。
Add your scores for questions one to nine to see how you score on the Negative Affectivity scale
卓越雇主排名:25
007系列电影主题曲第四名:汤姆·琼斯--《霹雳弹》

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

v. 借,供应货款,
“我们希望这份榜单会让大家采取措施保护自身的网络安全。”
最不淑女奖
Andrew Bargery, campus and schools engagement leader at PwC, says Teach First graduates stand out: “They have already worked in a professional envir-onment and have professional maturity and are good at building relationships.”

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Blue skies will not be, and should not be, a luxury.
'Cutie and the Boxer' was hardly noticed by the movie-going public, but a list of fine films isn't a rundown of box-office triumphs. The reach of Zachary Heinzerling's debut feature-length documentary is equaled by its grasp. On the surface it's about nothing more-or less-than a troubled marriage that has somehow managed to last 40 years. Beneath the surface, then startlingly out in the open, is a history of rivalry (both husband and wife are artists), enmity, reluctant devotion and, most startling of all, enduring love.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

这个领域的创新速度非常快。自从Fitbit于2008年成立以来,各家公司已经发布了五到六个完全不同的产品。三星(Samsung)则在九个月内发布了可穿戴设备Galaxy Gear的三到四个衍生产品。索尼(Sony)、Pebble、谷歌和Facebook的头戴式虚拟现实设备Oculus Rift也紧随其后。
adj. 仁慈的,(为)慈善事业的,宽恕的
过去一年中,亚利桑那州最大的赢家是建筑和休闲/酒店行业,这两个行业共增加了超过1万个就业机会。其他快速增长的行业包括商业服务、金融活动、教育和医疗服务。
The youngest on the list is 19-year-old Norwegain heiress Alexandra Andresen, who holds a 42 per cent stake in her family's business. Her 20-year-old sister is the second youngest on the list.
事实上,去往俄罗斯有许多可供选择的廉价航班。其国内的西伯利亚大铁路也使得交通十分便利。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Online peer-to-peer broker Ezubao previously cheated about 900,000 investors out of more than 50 billion RMB through a giant Ponzi scheme, the Xinhua News Agency reported in February.
Technically it is a project of the 10-member Association of Southeast Asian Nations to bring all of its trade deals in the region under one umbrella. It also lacks the ambition on many fronts of the TPP.
用户说,语音信息的传输速度很快,可以在微信平台上对话。但和微软(Microsoft Corp.)的Skype等免费语音应用不同的是,在微信上还可以另选时间回复别人发来的语音信息。北京微信用户Robin Wang说,我可以决定什么时候回复,以及回不回复。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 屡挫屡战 欧普照明IPO再上会
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

单词impresario 联想记忆:
“我跟她很像,我们真的就像一对老夫妇。”

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

一名姓苏的学生表示:“此外,大多数中国家庭只有一个孩子,所以为了和家人朋友离得近一些,大多数留学生都会选择回国。”他放弃了自己在英国的工作,回国照顾自己的母亲。
它基于针对各商学院及其2013年毕业的学员的调查。
"People can be unhappy for many reasons -- from poverty to unemployment to family breakdown to physical illness," the report said. "But in any particular society, chronic mental illness is a highly influential cause of misery. If we want a happier world, we need a completely new deal on mental health."

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

理由有两方面:首先,从逻辑上讲,你实在有太多的机会被人抓住你在搜索工作。简历的副本会被发现。计算机服务器会被检查。工作伙伴会从表面上或者情绪上(多半是后者)察觉到你为面试而心不在焉。
他们现在对阵克里夫兰和波士顿时的人员对位看起来顺眼多了。
我照顾好自己了吗?有时候,我们太过于关心他人从而忘记了去照顾自己。这很容易就把自己遗忘。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

与亨特相反,在《钢琴课》中与亨特联合主演的安娜·帕奎因(Anna Paquin),她的小金人似乎居无定所,游荡在她装袜子的抽屉和放靴子的地板之间。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

Despite such arguments from a handful of scientists, the vast majority of those who study the climate say the earth is in a long-term warming trend that is profoundly threatening and caused almost entirely by human activity.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

在全球前50名女富豪中,中国大陆的女企业家占56%。
需要快速发送大到2GB的大型文件?不妨试试WeTransfer.com。你甚至不需要建立账户,我几乎每天都用它传文件。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

['t?ksik]
为编制英国《金融时报》2017年金融硕士课程排行榜而收集的数据显示,在金融领域工作的毕业生当中,性别多样化程度日益上升。
rough
"It became an issue about so many things, such as the environment, energy, workplace disasters and the role of big government. It became a lightning rodfor peoples' anxieties," she explained.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

['letis]
梅瑟威一场拳赛的要价可以高达7000万英镑,但是他去年的收入只排在榜单上位居第16位。去年梅瑟威的拳赛收入达到了2000万英镑,此外他的服装品牌TMT(The Money Team)也给他贡献了500万英镑。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

他在文章中写道:“促进公平和多样性的保护措施不应该把个人的性取向排除在外。有些人不得不在工作时隐瞒自己的这些特征,这种现象已经存在了太长的时间,而且已经影响了太多的人。”
众所周知,蝙蝠侠的扮演者不再是克里斯汀·贝尔,而是肉肉的本·阿弗莱克。他将打败超人,拯救哥谭镇。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Paris (AFP) - Some 1,400 people living in France have either joined the jihadist cause in Syria and Iraq or are planning to do so, Prime Minister Manuel Valls said Monday.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

2010年英文新年祝福邮件
4.你的同事会泄密。
Mark Rutte, the Dutch prime minister whose People’s Party for Freedom and Democracy (VVD) is slightly ahead of the PVV, has seen his poll numbers rise in recent days because of his hardline stance with Ankara. On Tuesday he called Mr Erdogan’s comments “a disgusting distortion of history”, adding: “We will not lower ourselves to this level. It is totally unacceptable.”
The number of initial public offerings (IPO) and the amount of funds raised in the Chinese mainland's A-share market fell sharply year-on-year during the first half of 2016, according to statistics released by PwC last Monday.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

我的饮食健康吗?我们所吃的食物种类很大程度上会影响我们在身体和情绪上的感觉。食用过多垃圾食品会导致偏执,使人精力降低。反之,饮食健康则会使人有更好的情绪和更高涨的劲头。
我是否玩儿得太high了?缺乏实现某些事情的动机会让你失去平衡或者稍后会让你感到筋疲力尽,很有压力。休息一下是非常有必要的,但是如果你休息得过了头从而使生产力降低,或者你养成了太过拖拉的习惯,那么或许就需要时间来平衡你的时间安排,以便你可以完成大量的事情而仍有时间休息娱乐。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

1.戛纳也有软肋
As we ring in the New Year, let’s take stock of where we are at with the oil markets. 2014 proved to be a momentous one for the oil markets, having seen prices cut in half in just six months.
Remedy: This is another hindsight-based regret that you can’t cure without a time machine. The years, energy and dollars you spent on your degree are sunk costs. You can’t do anything about your past academic track record, but you can identify the areas in which you think you fell short in your college days and figure out how to augment those shortcomings in the present. For example, if you feel you didn’t do enough networking outside of the classroom, you might consider joining an alumni group or make a greater effort to participate in professional associations in your field. If you regret skipping your 8:00 AM managerial accounting class and mourn how useful those concepts would be to you now, check out the continuing ed options at your nearest community college.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

就目前来看,我觉得他们大概会在第十顺位,在这么低的顺位想要得到一个立即能够成为球队建队基石的新秀可不容易,并且留给鹈鹕队出成果的时间不多了。
5. 持续行动
这个领域的创新速度非常快。自从Fitbit于2008年成立以来,各家公司已经发布了五到六个完全不同的产品。三星(Samsung)则在九个月内发布了可穿戴设备Galaxy Gear的三到四个衍生产品。索尼(Sony)、Pebble、谷歌和Facebook的头戴式虚拟现实设备Oculus Rift也紧随其后。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
From the themed collection: 中望CAD结构提高建筑设计效率
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

这部13个小时的,关于长毛狗经历的影片花了45年才来到美国的影院,但时机却恰到好处。里维特先生淘气地在巴黎、法国文学与若干永恒的哲学谜题(真实的本质是什么,我们怎么知道我们知道,因与果之间的联系)之间徜徉,它既是一个迷人的,被重新发觉饿出来的艺术品,片长简直疯狂;与此同时,也警示着电影的未来。一切都已经做过了,一切都仍然是可能的。
Sam Smith is a fluid soul man, with style channeling Otis Redding, Aretha Franklin and Ray Charles alongside modern icons like Amy Winehouse and Adele.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

走上一段旋转楼梯就是几间卧室。中间有一处阁楼式的书房俯瞰着中庭。主卧套间和配套的浴室内有几面玻璃墙可以观赏数英亩湿地的景色。这个套间通往该房屋临水一侧的一个阳光平台。另外两间卧室也带有配套的浴室。底层已全部装修,用作健身房,并带有一间无洗浴功能的卫生间和一间可停放几辆车的车库。
双语:明星纹身爱用拉丁语 粉丝追捧学语言
去年年末,世界卫生组织宣布,寨卡病毒不再是全球紧急公共卫生事件。然而,人们才刚刚开始认识到这种病毒对婴儿及其未来几十年生活的影响。在巴西东北部,人们首次发现了病毒与小头畸形等出生缺陷之间的联系,家庭竭力为患病婴儿提供最好的生活。研究人员希望通过研究在巴西出生的一对双胞胎,来寻找病毒对胎儿影响的线索。这对双胞胎中,一个有出生缺陷,另一个没有。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

‘The Good Wife’ Once Will (Josh Charles), Alicia’s illicit love interest, died at the end of Season 5, this sexy CBS courtroom drama seemed as if it might droop and wither, but instead, the sixth season steamed with almost madcap energy, mixing Alicia’s newly fledged political campaign, a war of the roses between Alicia’s new firm and her old one, and the legal travails of Cary, her legal partner. Alicia isn’t quite so good anymore, and that makes “The Good Wife” all the better.
“…was snervous she almost fainted.”

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 工行6000亿融资支持租房市场
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

眼见克莱斯勒的市场份额呈现死亡式螺旋下降,菲亚特会最终认识到这个不中用的公司还真就是不中用了。预计菲亚特会在8月前扬言彻底和克莱斯勒分道扬镳,除非全美汽车工人联合会(UAW)和美国纳税人作出更多让步。
The prospect of a major shakeup right before the deadline is usually a recipe for disaster, especially if it leads to immediate roster change.
项目总成本:17.66万美元

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

The U.S. Veterans Day holiday also coincides with other World War One-era holidays around the world, including Remembrance Day in Britain and the Commonwealth nations of Australia and Canada.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Although the average punctuality rate of the surveyed airports rose 7% year-on-year to 70.4% in 2016, the average delay time was 33 minutes.
《不安感》

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

1.Bladeless Fans
大师级别的老式、线性的动作电影拍摄,充满污秽、朋克、反乌托邦的澳大利亚式幽默。也是最近除玛格丽特·阿斯特伍德(Margaret Atwood)的小说之外,最好的生态-女权-社会主义作品。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Besides Edhec and HEC, Essec Business School, ESCP Europe and Skema Business School are in third, fourth and sixth places respectively.
11月,中国的出口总值增速是预期的2倍多,这增加了中国的贸易顺差。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

“一带一路”战略:“丝绸之路经济带”和“21世纪海上丝绸之路”
The leadership changes across the industry will be of particular interest to female consulting professionals, given none of these firms have ever been run by a woman. Consulting firms are vocal proponents of the business case for improved gender diversity at the top of large companies. It will be interesting to see if any of them decide to practice what they preach.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

首先,Bitstamp遭遇黑客袭击,以及2011年黑客袭击比特币交易平台Mt. Gox(此次黑客袭击要严重得多,其损失当时约合4亿美元),往往被误解为比特币本身存在安全问题。但事实上,这只能表明上述比特币交易平台存在缺陷,而非比特币技术本身存在问题。而最令人激动的,正是比特币背后的底层技术。正如《财富》杂志2015年1月刊《打造未来》系列报道中所写,大部分极为看好比特币、为其大声疾呼的狂热粉丝(包括马克o安德森这样的大牌企业家,也包括花大把时间更新比特币REDDIT页面的开发者和比特币“矿工”),更感兴趣的是能建立在比特币“区块”(该货币基本骨架)上的应用,而非比特币货币体系。两个实体间可通过“区块”安全交换任何形式的价值。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

In this Jan. 6, 2004 file photo, Apple CEO Steve Jobs displays the at the Macworld Conference and Expo in San Francisco. Jobs,
vt. 鼓励,促进,支持
Sure, Chris Paul is a bit bigger and stronger now, but he still looks almost identical to the way he did in high school. He even had his trademark mustache back in high school.
Although Facebook is blocked in China, Tencent has linked WeChat to Facebook, which means that users outside of China can use the service in conjunction with the world's most popular social network. That is a boon for WeChat in Southeast Asian countries like Indonesia, Thailand and the Philippines, which have large numbers of Facebook users. Tencent has offered WeChat in languages for all three markets.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

对专业投资者而言,2014年最令人沮丧的一点是,美国经济复苏时断时续。2014年1月,经济领域捷报频传。然而,在短短几周内,一场暴风雪席卷全美,各种经济数据似乎也因此停摆。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 部分上市公司折价甩卖房产
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

For once, the Lakers are in good spot and don't have to rush into anything. Take some time. See what they have. They're not making the playoffs with that defense, but that's not really the point of this season anyway.
‘Jeopardy!’ This game show celebrated the 50th anniversary of its debut (broadcast on March 30, 1964), and proved it can still not only stump viewers but also surprise them. That’s not just because the host, Alex Trebek, briefly regrew a mustache after 13 clean-shaven years, but also because some contestants showed they could still rile an audience. This year, it was Arthur Chu, who introduced a blitzkrieg style of gamesmanship that provoked a cyber hate-fest. His strategy was thrilling and certainly effective: he came in second in the Tournament of Champions. (Ben Ingram, the nice guy, finished first.)
雇主因种族、肤色、性别、国籍、宗教、年龄或残疾而歧视员工属于违法行为。但美国多数州至今依然不保护LGBT群体的工作权益。苹果公司CEO蒂姆库克希望消除这种差异。11月份,库克在《华尔街日报》(Wall Street Journal )评论版对页发表了题为《平等就业对企业有益》(Workplace Equality Is Good for Business)的文章,敦促联邦立法,以免就业者因性取向而受到歧视。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

1.无叶风扇
I can't stop thinking that these children are my age, that it makes a tremendous difference where you are born, that I could be one of those children living in the Favellas of Rio; I could be a child starving in Somalia; a victim of war in the Middle East or a beggar in India. 我永远不能忘记这些和我同龄的孩子,当你出生的时候,他和我们真的很不相同,我也许生活在贫民窟,也可能是终日饿着肚子的小孩,也可能是中东战争的牺牲品,或者印度的小乞丐。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

苹果(Apple)正面临着市值跳水的窘境,苹果股价从去年9月至今已下跌了35%。众多卖方分析师纷纷献计献策,现在甚至有人建议苹果推出廉价iPhone。摩根士丹利(Morgan Stanley)公司的凯蒂?休伯蒂对中国这一全球最大的智能手机市场进行了分析,并给大家算了一笔账。
2018年特里萨梅(Theresa May)会继续担任英国首相吗

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

4. Fruit Mold

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

The system for ensuring responsibility is taken for poverty elimination will be effectively enforced, the strictest possible evaluations and assessments of poverty alleviation will be carried out, and stern measures will be taken to address deception, falsification, and the manipulation of numbers in poverty elimination work. We must see that the results of our poverty elimination earn the approval of our people and stand the test of time.
Well, that’s it, kids: we’re heading home. Chinese shares are down 7 per cent, and thanks to the newly-instituted market circuit breakers, that means the market shuts.
China’s outbound non-financial investment fell 40.9 per cent during the ten months through October, according to official figures, reflecting the enduring impact of strict capital controls.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 今年稳健货币政策的内涵没有变
Paper

Length-scale dependence of protein hydration-shell density

新年的祝福,平日的希冀,愿你心境祥和、充满爱意,愿你的世界全是美满,
1.The Military Parade
以美元计算的话,这一跌幅就更加明显了,上个月出口同比下滑11.2%至1774.8亿美元。这一跌幅不仅超过了去年12月1.4%的跌幅,也超过了下滑1.8%的预期。这是自去年3月下滑15%以来的最大跌幅。
Volatility in currency markets is also likely to be a factor for agricultural commodity prices in the next 12 months, with the euro likely to depreciate as a result of French, Dutch and German elections, Rabobank reckons.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

俄罗斯为世界上第十大经济体,除了天然气(碳氢化合物),经济贡献甚微。腐败和寻租行为使经济蒙受巨大损失。它依然沿用着苏联时代的基础设施,并且满足国民教育、医疗需求的能力正急速下滑。
[plein]

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

affected
[sju:'pri:m]
根据花旗居屋(Citi Habitats)提供的数据,在布鲁克林拟于明年投放市场的6527套新出租屋中,有1442套分布在贝德福德-斯图文森(Bedford-Stuyvesant)、布什维克(Bushwick)和克林顿山(Clinton Hill)。就在不久前,这些社区都还被视为不热门的地区。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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“现在黑客使用流行文化或体育活动中的常见说法来破解网上账户,因为他们知道很多人在使用这些容易记住的词做密码。”
2010年我们是否还会经历另一场“甲流”?

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